Thursday, August 31, 2006

Latest on Darfur

(via my son Ryan's blog: http://povertyfighters.blogspot.com/ )
Critical News!!!

This morning, the United Nations Security Council passed a
resolution authorizing a peacekeeping force in Darfur. The presence of
a peacekeeping force is the only measure that will provide the security
the people of Darfur desperately need.

This morning's vote is unmistakable evidence of the effectiveness
that the pressure you, and hundreds of thousands of Darfur activists
like you, have applied to world leaders. The international community
has shown that the will now exists to end the genocide in Darfur.

Yet, before peacekeepers can be deployed, the resolution says the Sudanese government must first agree to permit them.

This means that we cannot yet let up on the pressure.
One way to continue to make your voice heard is to attend the "Save
Darfur Now: Voices to End Genocide" rally and concert in New York
City's Central Park on September 17. Click here for more information.
If
you cannot make it to New York, there are other September 17 events
taking place all over the country and the world as part of a Global Day
for Darfur. For more information on US events, click here. And for more information on international events, click here.

As always, thank you for everything you do.

Wednesday, August 30, 2006

A Shout Out to "Change the World Kind of People."

This past summer I spent a week in Maryland visiting relatives and family. While there, I was fortunate to be selected to speak at a panel at a leadership conference, in which I met incredibly inspiring people, ranging from the mother of an autistic child, an AIDS activist from Cameroon, a consultant who helps place people with NGOs, a student activist at Yale etc...One of the common threads that we all discussed was that for many of us "our inspiration found us, instead of the other way around." Before our discussion I thought that this experience was unique to me with respect to my initially unplanned journey to Saudi Arabia, which lasted nearly a decade.

That period in Riyadh was a life-changing experience for me in many ways (that would require a separate blog post, or ?novel)...But, one of the most important lessons from that time was how many truly blind people there are in the world. I was fortunate to be part of a very intense effort at the largest eye hospital in the world (The King Khaled Eye Specialist Hospital) to "stamp out blindness in Asia Minor." Hence, my continued interest in international ophthalmology even though I have been back in the U.S. for nearly four years

Later that same week in Maryland, I met a friend of mine from college and her husband who have dedicated their post student lives to public health projects in the third world, including Vit A supplementation to prevent night-blindness (a great cause--speaking as an ophthalmologist). They have been living in Indonesia for the past five years and had just completed study on prenatal vitamin supplementation to pregnant women. The study involved over 30, 000 women.

I also have friends referenced before in this blog, who spent two years overseas doing mission work as ophthalmologists in Nigeria. I met them in Saudi Arabia, along with many of my most inspirational friends. Another example of such a friend from Saudi is an ex--airforce pilot, turned ophthalmologist, who has adopted five children (at last count) of mixed ethnicities.

I have been truly blessed to have had the privilege of the friendship of such great people.Every time I meet people like these, I feel refreshed, re energized and enthusiastic...

Thus I want to give
shout-out to my inspired friends who have dedicated tremendous effort to such altruistic causes...and who continue to inspire me...

Africa Adds to Miserable Rank of Child Workers

Watch the video and be glad that you don't live in Zambia...

LUSAKA, Zambia — The boulders here are hard enough that the scavengers who have taken over the abandoned quarry south of downtown prefer not to strike them directly with their hammers.

They heat the rocks first — with flaming tires, scrap plastic, even old rubber boots — so that the stones will fracture more easily.

At dusk, when three or four blazes spew choking black clouds across the huge pit, the quarry looks like a woodcut out of Dante.

A boy named Alone Banda works in this purgatory six days a week.

Nine years old, nearly lost in a hooded sweatshirt with a skateboarder on the chest, he takes football-size chunks of fractured rock and beats them into powder.

Lacking a hammer, he uses a thick steel bolt gripped in his right hand.

In a good week, he says, he can make enough powder to fill half a bag.

His grandmother, Mary Mulelema, sells each bag, to be used to make concrete, for 10,000 kwacha, less than $3. Often, she said, it is the difference between eating and going hungry...

In Chechen’s Humiliation, Questions on Rule of Law - New York Times

Watch this very disturbing video and be glad you don't live in Chechnya...

International News - New York Times: "Chechen security forces��� brutish acts, such as the torture of a woman accused of adultery, have gone unpunished.

* Video: Revival of Brutality in Chechnya"

How a Vaccine Search Ended in Triumph - New York Times

How a Vaccine Search Ended in Triumph - New York Times: "There are fascinating stories behind every advance in medicine, be it hand washing or brain surgery. But the 70-year history behind the creation of a vaccine against human papillomavirus, which causes cervical cancer, is more fraught than most with blind alleys, delicate moments, humor and triumph."

Tuesday, August 29, 2006

Ten Things to Learn This Year

An excellent distillation advice for working in the "real world" from the business guru, Guy Kawasaki...

Ten Things to Learn This School Year iStock_000000218096Small.gif I’m on the campus of UCSB this week at family camp, and it's inspired me to blog about what students should learn in order to prepare for the real world after graduation. This is an opportune time to broach this subject because the school year is about to begin, and careers can still be affected. First, take this little test about the state of your understanding of the real world right after you graduated from school.

Real Wages Fail to Match a Rise in Productivity - New York Times

Real Wages Fail to Match a Rise in Productivity - New York Times: "With the economy beginning to slow, the current expansion has a chance to become the first sustained period of economic growth since World War II that fails to offer a prolonged increase in real wages for most workers."

The Consumerist: Shoppers Bite Back

The Consumerist: Shoppers Bite Back: "Wanted: Singing, Kung-Fu Stewardesses"

What are the requirements to be a flight attendant? A cute wiggle. A superhuman patience with the bovanity of humankind. The ability to comfortably work for hours at a time in panty hose.

Those are all tall orders. But for prospective stewardesses for China's Sichuan Airlines, their chances of getting a coveted air hostess job got even harder: they need to know how to dance, sing and do kung-fu.

Monday, August 28, 2006

Clinical Cases and Images - Blog: What's New in General Internal Medicine?

Clinical Cases and Images - Blog: What's New in General Internal Medicine?: "The latest Update in General Internal Medicine is published in the Annals of Internal Medicine (PDFs free after 6 months). While the whole text is spread over 11 pages, I would like to summarize just a few things I found useful. Recommendations are divided in 3 groups: 'start', 'consider' and 'stop.'"

Psychology Today: The Hidden Side of Happiness

Psychology Today: The Hidden Side of Happiness: "The Hidden Side of Happiness
Pleasure only gets you so far. A rich, rewarding life often requires a messy battle with adversity.
By:Kathleen McGowan"

Web Guitar Wizard Revealed at Last - New York Times

Web Guitar Wizard Revealed at Last - New York Times: "EIGHT months ago a mysterious image showed up on YouTube, the video-sharing site that now shows more than 100 million videos a day. A sinewy figure in a swimming-pool-blue T-shirt, his eyes obscured by a beige baseball cap, was playing electric guitar. Sun poured through the window behind him; he played in a yellow haze. The video was called simply ���guitar.��� A black-and-white title card gave the performer���s name as funtwo."

Before the ���04 Tsunami, an Earthquake So Violent It Even Shook Gravity - New York Times

Before the ���04 Tsunami, an Earthquake So Violent It Even Shook Gravity - New York Times: "The giant earthquake that set off a devastating tsunami across the Indian Ocean in December 2004 disrupted the earth enough to change gravity and to deflect satellites passing hundreds of miles above."

Wednesday, August 23, 2006

Molecular Expressions: Science, Optics and You - Secret Worlds: The Universe Within - Interactive Java Tutorial

Molecular Expressions: Science, Optics and You - Secret Worlds: The Universe Within - Interactive Java Tutorial: "View the Milky Way at 10 million light years from the Earth. Then move through space towards the Earth in successive orders of magnitude until you reach a tall oak tree just outside the buildings of the National High Magnetic Field Laboratory in Tallahassee, Florida. After that, begin to move from the actual size of a leaf into a microscopic world that reveals leaf cell walls, the cell nucleus, chromatin, DNA and finally, into the subatomic universe of electrons and protons."

Mirage at the Bottom of the Pyramid | NextBillion.net - Development Through Enterprise

Mirage at the Bottom of the Pyramid | NextBillion.net - Development Through Enterprise: "Poor people ��� at the bottom of the pyramid (BOP) ��� represent a very attractive market opportunity. The ���BOP proposition��� argues that selling to the poor can simultaneously be profitable and help eradicate poverty. This is at best a harmless illusion and potentially a dangerous delusion. My recent paper shows that the BOP argument is riddled with fallacies, and proposes an alternative perspective on how the private sector can help alleviate poverty. Rather than focusing on the poor as consumers, we need to view the poor as producers. The only way to alleviate poverty is to raise the real income of the poor."

The Ad Starbucks Doesn't Want You To See... Because It Sucks. - Consumerist

The Ad Starbucks Doesn't Want You To See... Because It Sucks. - Consumerist: "The Ad Starbucks Doesn't Want You To See... Because It Sucks."

Blood on the tracks - The Boston Globe

Blood on the tracks - The Boston Globe: "David Hume wrote that reason is a ``slave to the emotions.' But new research suggests that in our moral decision-making, reason and emotion duke it out within the mind."


...the results should lead us to be skeptical about our snap moral decisions, however natural and obvious they seem, as they may be very much affected by the mood we happen to be in.

In Niger, Using Vacation to Help the World’s Poor

Beats Disneyland :)...

That was the start of a two-week trip to a nation that the New York Times columnist Nicholas D. Kristof recently called “the most wretched country in the world,” and a venture that grew out of a question our 16-year-old daughter, Leslie Brian, posed after hearing yet another news account of suffering in Africa.


“So, is there anything we can do about it?” she had asked.

For seven nights during an extended spring break, our family joined Wodaabe and Tuareg nomads in the Niger desert in an immersion experience offered through a small nonprofit organization, the Nomad Foundation of Ojai, Calif. Our itinerary hinted at the remoteness of our destination: “Most of these locations refer to wells and will not mean much to anybody but the people who live there.”

Tuesday, August 22, 2006

Princeton University - Snap judgments decide a face's character, psychologist finds

Princeton University - Snap judgments decide a face's character, psychologist finds: "We may be taught not to judge a book by its cover, but when we see a new face, our brains decide whether a person is attractive and trustworthy within a tenth of a second, according to recent Princeton research. "

Immune System Might Be Revived in Patients

A spirited race between top immunology teams is set to culminate today with the publication of two scientific papers reaching broadly similar conclusions about the AIDS virus: It exploits the human body's natural mechanism for shutting down the immune system, and the process can be reversed.

The findings raise the tantalizing possibility that doctors one day could switch a patient's immune system back on, so that it could resume its fight against HIV, or even cancer cells, certain parasites or the virus that causes hepatitis C. Those very different diseases "have one common denominator," says Anthony Fauci, director of the National Institute for Allergy and Infectious Diseases. "They persist. They're chronic."
(..)

Nevertheless, research in this area is exploding. The Bill and Melinda Gates Foundation is funding a team researching how to turn the immune system back on in hepatitis C patients. Researchers at the National Institutes of Health are studying PD-1 in tuberculosis, one of the world's leading killers.

"This isn't just HIV," says Harvard University immunologist Bruce Walker, the lead researcher on the study published in Nature. "This is much broader."

Research has progressed furthest in cancer, where scientists have shown that PD-1 can shut down immune responses when it is activated by certain types of tumor cells.
(..)

The research being published today goes further to address one of the most vexing mysteries in the biology of AIDS. Key immune-system cells known as HIV-specific CD8 killer T-cells exist in high numbers in many HIV-infected patients. Early in the course of the infection, these cells kill other cells carrying the virus. But in long-term patients, these cells barely fight the virus at all. The reigning theory was that HIV somehow disabled them. That may still be true in part, but today's studies reveal that HIV actually exploits the body's own mechanism for shutting the cells down.

The PD-1 molecule buds on the surface of the killer T-cells that target HIV. By itself, PD-1 is inert and does nothing. But when PD-1 encounters a partner molecule, or ligand, the interaction sets off a chain reaction inside the killer T-cells. The T-cells multiply much more slowly or not at all, and overall they secrete far less of their powerful cytokines, the researchers found. Essentially, they abandon the fight.

Malaria's Toll

Malaria's Toll
By JASON L. RILEY
August 21, 2006; Page A11

Each year, malaria afflicts a half-billion people (roughly the population of North America) and kills a million of them
(roughly the population of San Jose). And the latter is a low-end estimate. The actual number of fatalities is hard to pin down, since a body initially weakened by malaria becomes predisposed to other maladies.

But we do know that malarial mosquitoes are attracted to the tropical climes of sub-Saharan Africa, where they prey on impoverished populations that lack the sprays, screens and bed nets necessary to keep the insects at bay. Hence, some 75% of malaria victims are African pregnant women and children under five.

The economist William Easterly calculates that medicine that would prevent half of all malaria deaths costs only $0.12 a dose, and bed nets that would severely limit new cases cost a mere $4 apiece. "Preventing five million child deaths over the next ten years would cost just three dollars for each new mother," he writes in his book "The White Man's Burden."

Mr. Easterly argues that the tragic incompetence of the Western foreign aid industry -- $2.3 trillion spent, over five decades, but little forward advance -- stems from its overly bureaucratic approach to problem-solving. Agencies like the World Health Organization, the Global Fund and the World Bank traditionally have been staffed by well-meaning "planners," to use his term, who see "poverty as a technical engineering problem that [their] answers will solve."

What these organizations really need, says Mr. Easterly, are more of what he calls "searchers," or people who understand that "poverty is a complicated tangle of political, social, historical, institutional and technological factors." Where planners raise high expectations but take no responsibility for meeting them, searchers prefer to work case-by-case, using trial and error to tailor solutions to individual problems, fully aware that most remedies must be homegrown.
[Lance Laifer]

Lance Laifer, a hedge-fund manager in Connecticut, is a searcher. The horrors of malaria came to his attention in May 2005 via a Charlie Rose interview with Columbia University's Jeffrey Sachs, the development expert (and quintessential planner). "I didn't know anything about malaria," Mr. Laifer said in a recent interview. "I didn't know it still existed. I didn't know it was still killing people. I thought it was eradicated a long time ago. I was just flabbergasted."

(..)

Mr. Laifer turned his outrage into something of an obsession. He began researching malaria intensely; and he also ran some numbers. Bed nets, medications, insecticide, swamp drainage, etc., came to less than $10,000 for a typical African village of 1,000 people. "That's a doable number," Mr. Laifer concluded.

And then he picked up the phone, turning to friends and associates who help him organize an annual fundraiser to fight cancer. "I basically had a group of people that I know have very big hearts in this area, specifically in dealing with children," he says. "So I called them and said, 'What do you know about malaria and how many people are dying from it?'"

That was the starting point. Where it will end is anyone's guess. Inside of a year, and working with George Ayittey of the Free Africa Foundation, Mr. Laifer's efforts have spawned five "malaria-free zones" in Ghana, Nigeria and Kenya. Expansion to Ivory Coast and Benin is in the works. He adds that he has the financing to roll out additional zones this year but -- ever the searcher -- first wants to assess what's working and what isn't. If all is going well, "next year I see us doing something like 100 villages."

Mr. Laifer says a future focus will also be DDT, the pesticide used by Americans and Europeans in the 1940s to win domestic fights against malarial mosquitoes. Indoor spraying of DDT is by far the cheapest and most effective way to control the disease. One South Africa province employing DDT saw malaria infections and deaths drop 96% over a three-year span.
(..)

African nations, fearful that lucrative European and U.S. markets might ban their agricultural exports, make do with less-effective DDT substitutes. Though DDT, like any chemical, can be harmful in high doses, there's no evidence that using it in the amounts needed to combat malaria has any ill-effect whatsoever on humans.
(..)

But Mr. Bate says the reality is that economic development is the only sure-fire anti-malaria strategy. "We eradicated malaria in Malaysia in the '50s and '60s, and in Singapore at the same time. It came back in Malaysia in the '70s but not in Singapore, and the reason it came back is that there wasn't enough wealth for people to have screens on the windows. Singapore's economy, however, grew rapidly, and there isn't a problem there anymore."

Which is why sub-Saharan Africa's poverty and poor infrastructure make it such a difficult case. And why widespread health problems will persist in the region until people are no longer living under exposed conditions and able to get proper treatment. Not that Mr. Laifer is bowed by these challenges. "All I'm trying to do is give these kids their lives back," he says. "Somebody needs to do this."
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