Disease Risk Depends on Which Parent a DNA Variant Is Inherited From

Icelandic biologists have discovered that the genetic risk of several common diseases, like Type 2 diabetes and cancer, can depend on which parent a DNA variant is inherited from.
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Another explanation is that the missing heritability lies in aspects of cell biology that are not yet understood.

Decode scientists have found one such instance. They report in Friday’s Nature that a DNA variant increases a person’s risk of Type 2 diabetes by 30 percent if inherited from the father, but reduces the risk by 10 percent if comes from the mother.