Wednesday, May 08, 2013

One hospital charges $8,000 — another, $38,000

In the actual article from the Washington Post, there is an interactive module in which you can insert the name of your state and see how your state compares to national averages for common surgical procedures...
Uvealblues

Consumers on Wednesday will finally get some answers about one of modern life’s most persistent mysteries: how much medical care actually costs.
For the first time, the federal government will release the prices that hospitals charge for the 100 most common inpatient procedures. Until now, these charges have been closely held by facilities that see a competitive advantage in shielding their fees from competitors. What the numbers reveal is a health-care system with tremendous, seemingly random variation in the costs of services.


Link

Tuesday, April 30, 2013

A Sense of Where You Are


The workings of the grid cells show that in the brain “you are constantly creating a map of the outside world,” said Cori Bargmann, of Rockefeller University, who is one of the two leaders of a committee set up to plan the National Institutes of Health’s contribution to President Obama’s recently announced neuroscience initiative.
Often, the workings of billions of neurons that produce our thoughts are opaque. But electrical recordings of signals emitted by grid cells show a map “with a framework and coordinates that are completely intuitive,” Dr. Bargmann said. And to find such a straightforward system is, in its own way, “just mind-boggling.” What is the brain doing being so mysteriously unmysterious?
The implications of the discovery are both practical and profound. The cells have been proved to exist in primates, and scientists think they will be found in all mammals, including humans. The area in the brain that contains the grid cell navigation system is often damaged early in Alzheimer’s disease, and one of the frequent early symptoms of Alzheimer’s patients is that they get lost. The Mosers do not work on humans, but any clues to understanding how memory and cognitive ability are lost are important.

Sunday, April 28, 2013

Hammurabi’s Code and U.S. Health Care

Interesting that the economist, Uwe Reinhardt, opted for citation of eye surgery in this article!
There are also some good letters to the editor at the end of the article... (hit the link button below)
UvealBlues


Sometime around 1780-70 B.C., the Babylonian King Hammurabi promulgated the now famous Code of Hammurabi, covering both civil and criminal law.
TODAY’S ECONOMIST
Perspectives from expert contributors.
The code is said to have informed both Jewish and Islamic law. Remarkably, it has echoes also in modern health policy in the United States.
Among the 282 laws in Hammurabi’s Code, nine (215 to 223) pertain to medical practice:
215. If a physician make a large incision with an operating knife and cure it, or if he open a tumor (over the eye) with an operating knife, and saves the eye, he shall receive 10 shekels in money.
                216. If the patient be a freed man, he receives five shekels.



(..)
Not all of these laws have survived the millennia. Relative to Hammurabi’s draconian medical malpractice code, for example, modern medical malpractice penalties represent mere slaps on the wrist.
On the other hand, our modern, differentiated payment system for health care does resemble the Code of Hammurabi in some respects.
To illustrate, for a primary care office visit with a new patient of 30-minute duration (using Current Procedural Terminology, or C.T.P. codes, in this case Code 99203), New Jersey’s Medicaid in 2012 paid a nonspecialist $25 and a board-certified specialist $32.30. The comparable fees paid physicians for commercially insured patients are jealously guarded trade secrets, but it is reasonable to assume them to be $100 to $200. Other fees in the C.P.T. code are similarly low for Medicaid.
(..)
Physicians clearly understand this relative valuation being signaled to them. According to a recent estimate, almost a third of American physicians are unwilling to accept any new patients covered by Medicaid. In New Jersey in 2011, only 40 percent of physicians accepted new Medicaid patients (seeExhibit 4). Given the insulting valuations many state Medicaid programs put upon the physicians’ work, that’s understandable.

Friday, April 26, 2013

Doctors Denounce Cancer Drug Prices of $100,000 a Year


These same cost issues described in the article below apply to drugs used in treating retinal disease, in which companies charge 2000-3000$ per injection. Some patients need these monthly...and in each eye...for the rest of their life...
Uvealblues

With the cost of some lifesaving cancer drugs exceeding $100,000 a year, more than 100 influential cancer specialists from around the world have taken the unusual step of banding together in hopes of persuading some leading pharmaceutical companies to bring prices down.
(..)
Prices for cancer drugs have been part of the debate over health care costs for several years — and recently led to a public protest from doctors at a major cancer center in New York. But the decision by so many specialists, from more than 15 countries on five continents, to join the effort is a sign that doctors, who are on the front lines of caring for patients, are now taking a more active role in resisting high prices. In this case, some of the specialists even include researchers with close ties to the pharmaceutical industry. 

Eggs, Too, May Provoke Bacteria to Raise Heart Risk


For the second time in a matter of weeks, a group of researchers reported a link between the food people eat and bacteria in the intestines that can increase the risk of heart attacks.
The lecithin study, published Wednesday in The New England Journal of Medicine, is part of a growing appreciation of the role the body’s bacteria play in health and disease. With heart disease, investigators have long focused on the role of diet and heart disease, but expanding the scrutiny to bacteria adds a new dimension.
Heart disease perhaps involves microbes in our gut,” said the study’s lead researcher, Dr. Stanley Hazen, chairman of the department of cellular and molecular medicine at the Cleveland Clinic Lerner Research Institute. 
(..)
To show the effect of eggs on TMAO, Dr. Hazen asked volunteers to eat two hard-boiled eggs. They ended up with more TMAO in their blood. But if they first took an antibiotic to wipe out intestinal bacteria, eggs did not have that effect.
To see the effects of TMAO on cardiovascular risk, the investigators studied 4,000 people who had been seen at the Cleveland Clinic. The more TMAO in their blood, the more likely they were to have a heart attack or stroke in the ensuing three years. 

Sunday, April 21, 2013

Why listening to music is as good as sex: Scientists say listening to tunes stimulates the senses giving pleasure

Why listening to music is as good as sex: Scientists say listening to tunes stimulates the senses giving pleasure

  • The more the listener enjoyed what they were hearing, the stronger the connections were
  • Researchers even say they can predict whether we will buy a song based on the reaction of our brain


  • Read more: http://www.dailymail.co.uk/sciencetech/article-2308020/How-listening-new-music-really-CAN-make-happy-Scientists-say-hearing-new-tunes-rewarding.html#ixzz2R7XONLYr

    Tuesday, April 16, 2013

    'ReadingMate’ reduces treadmill eye bobble

    PURDUE (US) — New technology makes it easier for aspiring multi-taskers to read while they run on thetreadmill.
    Link

    The Wikipedia of Biomarkers: Interview with Jean-Emmanuel Bibault and Charles Ferté, Co-Founders of CancerDriver


    Every year nearly 13 million people in the world are diagnosed with cancer. 7.6 million die from it, making it the leading cause of death in developed countries and the second leading cause of death in the developing world.
    While cures for cancer are hard to come by, there are promising avenues for diagnosis. Cancer biomarkers are one of them; they are molecular aberrations found in the tumors that predict the aggressiveness of a disease or the response to a treatment. Unfortunately, too few patients are tested for biomarkers and too many with identified biomarkers are not referred to the right drug or the right trial.
    Enter CancerDriver, a free repository of cancer biomarkers intended to improve access to biomarker information for patients, physicians, researchers, and pharmaceutical companies. CancerDriver contains a database of all known biomarkers in oncology. It can be found on the web and soon on iOS and Android mobile platforms.
    We had a chance to speak with Jean-Emmanuel Bibault and Charles Ferté, Co-Founders of CancerDriver, to discuss this revolutionary site.

    Tuesday, April 09, 2013

    Doctors driven to bankruptcy


    As many doctors struggle to keep their practices financially sound,some are buckling under money woes and being pushed into bankruptcy.

    Monday, April 08, 2013

    The Surprising Truth About 8 Common Diet Strategies

    Who has the time to keep up with weight-loss research? It's so technical...and confusing...and often contradictory! And yet if you don't know what's going on in the world of calorie counting, you may not be seeing the pounds drop off as fast as you think they should. In one European diet-and-exercise study, for example, participants who were given detailed explanations of the research itself were more likely to improve (exercise more or eat better or both) than a less clued-in group. Fortunately, we have dug into the latest research. And as we did, we noted that a surprising number of dieting tactics accepted as gospel have recently been shown to be dead wrong. Knowing which still hold up and which are big (fat) lies can mean the difference between winning and losing at weight loss.

    Sunday, April 07, 2013

    Culprit in Heart Disease Goes Beyond Meat’s Fat


    The researchers had come to believe that what damaged hearts was not just the thick edge of fat on steaks, or the delectable marbling of their tender interiors. In fact, these scientists suspected that saturated fat andcholesterol made only a minor contribution to the increased amount of heart disease seen in red-meat eaters. The real culprit, they proposed, was a little-studied chemical that is burped out by bacteria in the intestines after people eat red meat. It is quickly converted by the liver into yet another little-studied chemical called TMAO that gets into the blood and increases the risk of heart disease.
    That, at least, was the theory. So the question that morning was: Would a burst of TMAO show up in people’s blood after they ate steak? And would the same thing happen to a vegan who had not eaten meat for at least a year and who consumed the same meal?
    The answers were: yes, there was a TMAO burst in the five meat eaters; and no, the vegan did not have it. And TMAO levels turned out to predict heart attack risk in humans, the researchers found

    Patient people mull over future rewards

    Brain imaging suggests impulsive people don’t think about the reward they’ll get for waiting, whereas patient people seem to enjoy it.
    Link

    Friday, April 05, 2013

    A Beautiful Multimedia Newspaper Exposes Life In The World’s Largest Refugee Camp

    The Dadaab Stories site gives you a window into daily life in the African camp, home to 500,000 Somali refugees. But it’s not Western filmmakers making sob stories: The site is reported by the refugees themselves.
    Link

    The 4 Ideas That Melinda Gates Thinks Are Changing The World

    For the past three years, the Bill and Melinda Gates Foundation has hosted TEDxChange, a TEDx event with the goal of spurring action around the ideas supported by the foundation. This year, host Melinda Gates introduced seven speakers-- a theologian talking about faith and family planning, and children featured in the film The Revolutionary Optimists--who all discussed topics related to the event’s theme of "positive disruption." We talked to her after the event to learn more about some of the things happening around the world that Gates considers to be most disruptive--in a good way.
    Link

    In Sign of Warming, 1,600 Years of Ice in Andes Melted in 25 Years

    Glacial ice in the Peruvian Andes that took at least 1,600 years to form has melted in just 25 years, scientists reported Thursday, the latest indication that the recent spike in global temperatures has thrown the natural world out of balance.
    The evidence comes from a remarkable find at the margins of theQuelccaya ice cap in Peru, the world’s largest tropical ice sheet. Rapid melting there in the modern era is uncovering plants that were locked in a deep freeze when the glacier advanced many thousands of years ago.
    Link

    Thursday, April 04, 2013

    Our Inconsistent Ethical Instincts


    MORAL quandaries often pit concerns about principles against concerns about practical consequences. Should we ban assault rifles and large sodas, restricting people’s liberties for the sake of physical health and safety? Should we allow drone killings or torture, if violating one person’s rights could save a thousand lives?
    We like to believe that the principled side of the equation is rooted in deep, reasoned conviction. But a growing wealth of research shows that those values often prove to be finicky, inconsistent intuitions, swayed by ethically irrelevant factors. What you say now you might disagree with in five minutes. And such wavering has implications for both public policy and our personal lives.
    Philosophers and psychologists often distinguish between two ethical frameworks. A utilitarian perspective evaluates an action purely by its consequences. If it does good, it’s good.
    A deontological approach, meanwhile, also takes into account aspects of the action itself, like whether it adheres to certain rules. Do not kill, even if killing does good.
    No one adheres strictly to either philosophy, and it turns out we can be nudged one way or the other for illogical reasons.

    Tuesday, April 02, 2013

    Optimal Music for the Gym


    Researchers Say The Right Tempo Boosts Stamina, Energy Efficiency

    Link
    Research has found that at the right tempo, music can reduce the sense of exertion as well as boost motivation. Costas Karageorghis, deputy head of research at the School of Sport and Education at London's Brunel University, says the "sweet spot" for workout music is between 125 and 140 beats per minute when people aren't trying to time their movements to the music. Previously, experts believed that the faster a person exercises, the faster the music tempo should be.
    Other new studies have shown that when athletes synchronize their movements to a musical beat, their bodies can handle more exertion: Treadmill walkers had greater stamina and cyclists required less oxygen uptake. And swimmers who listened to music during races finished faster than others who didn't.

    Friday, March 29, 2013

    You're Eye-to-Eye With a Whale in the Ocean. What Does It See?

    A deep dive into how the most intelligent creatures in the ocean perceive their world.
    Link

    Could Some of Our Favorite Flavorings Be Damaging Our DNA?


    Plants are all-natural sources of all things good for us, right? It turns out some of our favorite plant-based flavorings may do more harm than good.
    Scientists from Johns Hopkins Kimmel Cancer Center report in the journal Food and Chemical Toxicology that teas, coffees and “smoky flavoring” could be damaging our DNA at levels comparable to that caused by chemotherapy drugs.


    Read more: http://healthland.time.com/2013/03/29/could-some-of-our-favorite-flavorings-be-damaging-our-dna/#ixzz2Ow8NfgIV

    Thursday, March 28, 2013

    Huge cancer study uncovers 74 genetic risk factors

    One of the largest cancer genetics studies ever conducted adds a wealth of information about the disease, but also highlights continuing difficulties with predicting cancer risk.
    (..)

    The studies found 74 new SNPs linked to the cancers, doubling the known common risk variants linked to them. It also found that many were linked to more than one cancer.
    “This indicates common underlying functional mechanisms at some of these susceptibility loci, and could lead to the identification of common biomarkers and therapeutic targets for intervention across several disease sites,” says geneticist Simon Gayther of the University of Southern California in Los Angeles.

    Long way to go

    But most of the common genetic risk factors for these cancers remain unknown. The COGS researchers estimate that they can now account for just 28% of the risk of familial breast cancer, 4% of the risk of ovarian cancer and 30% of the risk of prostate cancer123. Just asking whether a woman has any relatives with breast cancer still reveals as much about her risk of developing the disease as would surveying her SNPs.
    Hat tip to Ryan Dhindsa

    Easing Brain Fatigue With a Walk in the Park

    Scientists have known for some time that the human brain’s ability to stay calm and focused is limited and can be overwhelmed by the constant noise and hectic, jangling demands of city living, sometimes resulting in a condition informally known as brain fatigue.
    With brain fatigue, you are easily distracted, forgetful and mentally flighty — or, in other words, me.
    But an innovative new study from Scotland suggests that you can ease brain fatigue simply by strolling through a leafy park.
    Link

    Wednesday, March 27, 2013

    The Destructive Influence of Imaginary Peers

    We humans irrationally think we’re rational. We think that we decide how to behave by weighing the pros and cons. In reality, the strongest influence on our decisions is the example of the people around us — even, oddly enough, when they are imaginary.

    (..)

     Bad behavior is usually more visible than good.  It’s what people talk about, it’s what the news media report on, it’s what experts focus on.  Experts are always trying to change bad behavior by warning of how widespread it is, and they take any opportunity to label it a crisis.  “The field loves talking about the problems because it generates political and economic support,” said Perkins.

    This strategy might feel effective, but it’s not — it simply communicates that bad behavior is the social norm. Telling people to go against their peer group never works.  A better strategy is the reverse:  give people credible evidence that among their peers, good behavior is the social norm.
    (..)
    With social norming, you don’t tell anybody what to do.  You just tell them what people like them are doing. It’s a bit like the positive deviance approach I wrote about in February:  your focus is on spreading the word about what a community is doing right.
    One of the most important keys to making social norming work is salience. “We can only hold one thing in consciousness at a time – and it is that thing that drives behavior,” said Cialdini, who is writing his next book about the topic. Success is more likely if the social norming message hits people just when they are about to make that behavioral decision.

    Link

    Myanmar Jarred by Peace Laureate at Military Parade

    BANGKOK — Myanmar’s military asserted its role in the country’s politics at a ceremony on Wednesday that featured a prominent guest, Daw Aung San Suu Kyi, the Nobel laureate, whose presence among the generals would have been unthinkable a few years ago.

    Link

    Bacteria in the Intestines May Help Tip the Bathroom Scale, Studies Show

    Bacteria in the Intestines May Help Tip the Bathroom Scale, Studies Show

     The bacterial makeup of the intestines may help determine whether people gain weight or lose it, according to two new studies, one in humans and one in mice. 

    The research also suggests that a popular weight-loss operation, gastric bypass, which shrinks the stomach and rearranges the intestines, seems to work in part by shifting the balance of bacteria in the digestive tract. People who have the surgery generally lose 65 percent to 75 percent of their excess weight, but scientists have not fully understood why. Now, the researchers are saying that bacterial changes may account for 20 percent of the weight loss.
    The findings mean that eventually, treatments that adjust the microbe levels, or “microbiota,” in the gut may be developed to help people lose weight without surgery, said Dr. Lee M. Kaplan, director of the obesity, metabolism and nutrition institute at the Massachusetts General Hospital, and an author of a study published Wednesday in Science Translational Medicine.

    Link

    Docs channel MacGyver, turning iPhone into a microscope to diagnose parasites


    T
    ORONTO - It's an accomplishment worthy of MacGyver.
    Armed with only a mobile phone, some double-sided tape, a cheap ball lens and a flashlight, some doctors have jerry-rigged a microscope capable of diagnosing intestinal parasites in Tanzanian children.
    (..)
    Infection rates can be particularly high in poor, remote regions of developing countries. Children afflicted by these worms can suffer from chronic anemia and malnutrition, which can stunt physical growth and mental development.
    To look for the eggs that develop into these parasites, the scientists typically smear a small amount of stool on a glass slide, cover it with a second, and study the magnified image using a light microscope. Those cost about $200 and require electricity — which is not a constant in some settings.
    So Bogoch and his colleagues affixed an $8 ball lens to the camera lens of an iPhone, using double-sided tape. They propped slides over a cheap flashlight and examined the magnified image with the adapted iPhone's camera.

    Can You Smell Obesity?


    According to the latest research, it may be on your breath.
    It turns out that obesity may be detectable as a gas, thanks to organisms that inhabit our gut. In a study published in the Journal of Clinical Endocrinology & Metabolism, researchers extend our knowledge about the hidden universe of the microbes that live within us to show that obesity is associated with certain populations of microbes that give off a distinctive gas.


    Read more: http://healthland.time.com/2013/03/27/can-you-smell-obesity/#ixzz2OkdrAbwz


    When the Box Says 'Protein,' Shoppers Say 'I'll Take It'

    Protein is the buzzword that is helping sell many kinds of foods. Food companies are placing more prominent protein labels on packaging and adding protein to such products as drinks, bars and cereals.
    "It's one of those rare things that has a lot of different meanings to a lot of different people and they are all positive," says Barry Calpino, vice president of breakthrough innovation for Kraft Foods Group Inc., KRFT -0.92%sellers of products from Velveeta to Planters Nuts.
    (..)
    A label that says protein has what researchers call a "health halo effect" that goes beyond just the promise of protein. When people see the word, they also believe the product will make them feel more full or give them energy.
    (..)
    When people eat food that promises to be a good source of whole grains, fiber or protein "it makes you feel smart as a consumer that you've done something good for yourself," says Doug VanDeVelde, senior vice president of food marketing and innovation for Kellogg's.
    Link

    Tuesday, March 26, 2013

    In Africa, food staple toxin debilitates kids

    MICHIGAN STATE (US) — Poorly processed cassava, a food staple in much of sub-Saharan Africa, afflicts as many as tens of millions of children with konzo, a disease with devastating physical and cognitive effects.

    Link

    Salesmen in the Surgical Suite

    ..It is not the first time patients have claimed they were harmed by Intuitive’s robotic surgical equipment, called the da Vinci Surgical System. But the Taylor case, set for trial in April, is unusual. Internal company e-mails, provided to The New York Times by lawyers for the Taylor estate, offer a glimpse into the aggressive tactics used to market high-tech medical devices and raise questions about the quality of training provided to doctors before they use new equipment on patients.
    Link

    Monday, March 25, 2013

    Your Phone vs. Your Heart

    CAN you remember the last time you were in a public space in America and didn’t notice that half the people around you were bent over a digital screen, thumbing a connection to somewhere else?

    ost of us are well aware of the convenience that instant electronic access provides. Less has been said about the costs. Research that my colleagues and I have just completed, to be published in a forthcoming issue of Psychological Science, suggests that one measurable toll may be on our biological capacity to connect with other people.
    Our ingrained habits change us. Neurons that fire together, wire together, neuroscientists like to say, reflecting the increasing evidence that experiences leave imprints on our neural pathways, a phenomenon called neuroplasticity. Any habit molds the very structure of your brain in ways that strengthen your proclivity for that habit.

    Sunday, March 24, 2013

    The Brains of the Animal Kingdom


    New research shows that we have grossly underestimated both the scope and the scale of animal intelligence. Primatologist Frans de Waal on memory-champ chimps, tool-using elephants and rats capable of empathy.

    (..)
    A growing body of evidence shows, however, that we have grossly underestimated both the scope and the scale of animal intelligence. Can an octopus use tools? Do chimpanzees have a sense of fairness? Can birds guess what others know? Do rats feel empathy for their friends? Just a few decades ago we would have answered "no" to all such questions. Now we're not so sure.
    Experiments with animals have long been handicapped by our anthropocentric attitude: We often test them in ways that work fine with humans but not so well with other species. Scientists are now finally meeting animals on their own terms instead of treating them like furry (or feathery) humans, and this shift is fundamentally reshaping our understanding.
    (..)
    We also may need to rethink the physiology of intelligence. Take the octopus. In captivity, these animals recognize their caretakers and learn to open pill bottles protected by childproof caps—a task with which many humans struggle. Their brains are indeed the largest among invertebrates, but the explanation for their extraordinary skills may lie elsewhere. It seems that these animals think, literally, outside the box of the brain.
    Octopuses have hundreds of suckers, each one equipped with its own ganglion with thousands of neurons. These "mini-brains" are interconnected, making for a widely distributed nervous system. That is why a severed octopus arm may crawl on its own and even pick up food.
    Similarly, when an octopus changes skin color in self-defense, such as by mimicking a poisonous sea snake, the decision may come not from central command but from the skin itself. A 2010 study found gene sequences in the skin of cuttlefish similar to those in the eye's retina. Could it be: an organism with a seeing skin and eight thinking arms?


    Saturday, March 23, 2013

    Washed Away

    This review in the NY Times by Cheryl Strayed  is deeply affecting...Will be getting this book...Uvealblues

    Sonali Deraniyagala’s extraordinary memoir, “Wave,” opens on the morning of Dec. 26, 2004, as the author putters around a Sri Lankan beach-side hotel with her family. By chapter’s end she’s pantless, half-drowned, bleeding, bruised and numbly resistant to what she’ll soon be forced to know: The five people she loves most in the world are dead. Her two young sons. Her husband. Her parents. All of them killed by a force she can’t yet comprehend, though she was caught up in it and nearly killed by it too. She only knows that “something came for us.” It was, as she and the world will soon learn, a tsunami of epic scale that took an estimated 230,000 lives across a dozen countries.

    So begins the most exceptional book about grief I’ve ever read. In prose that’s immaculately unsentimental and raggedly intimate, Deraniyagala takes us deep into her unfathomable loss.
    (..)
    That she allows us to experience that same alertness without smothering us in sorrow is the miracle of this beautiful book. I was thunderstruck by Deraniyagala’s loss, yes, but most of all by her ability to reveal the whole “outlandish truth” of her grief, to write about a tragedy so bewilderingly complete that, nearly a decade out, “it still seems far-fetched, my story, even to me

    Link

    Thursday, March 21, 2013

    21 Extreme Close Ups of the Human Eye



    Born in 1976, Suren Manvelyan started to photograph when he was sixteen and became a professional photographer in 2006. His photographic interests span from Macro to Portraits, Creative photo projects, Landscape, and much more. Suren’s photos have been published in numerous magazines and newspapers in Armenia and worldwide.
    His project, entitled Your beautiful eyes, is currently the most viewed project of all time on Behance with 2,999,655 views and is the second most ‘appreciated’ project of all time with 70,140 likes.

    10 Detailed Close-Ups of Animal Eyes



    We’ve already featured the incredible macro photography of Suren Manvelyan before, showcasing his series on human eyes. This time we check out Suren’s masterful collection of animal eye close-ups. While this post and the one prior focus on Suren’s macro work, his talent spans to portraits, landscapes and other creative photo projects which you can see on his personal website and portfolio on Behance.
    Lama

    Wednesday, March 20, 2013

    Violins ‘sing’ in multiple languages

    TEXAS A&M (US) —When creating violins, the Italian masters Stradivari and Guarneri tried to impart specific vowel sounds to the instruments, but new research shows only two of the vowels were in their native language.

    Friday, March 15, 2013

    Personalized Brain Transplants: Skin Cells to Brain Cells Achieved in Primates

    This stem cell technology could have great utility in a wide variety of retinal disease..
    Uvealblues

    In many ways the Holy Grail in transplantation is to convert a body’s own cells into stem cells, turn those into neural cells, and then integrate them into functional circuitry within the brain. Until now, only pieces of that puzzle have been possible. Su-Chun Zhang, who was the first to convert embryonic stem cells (ESCs), and later induced pluripotent stem cells (iPSCs) into neurons, has now demonstrated that these iPSCs can be successfully introduced into the brain — in other words, he has achieved autologous (self to self), tumorless, indefinite, and functional neuro-transplantation.
    Link

    Ten Bets You Will Always Win

    Professor Richard Wiseman, creator of the popular "10 Bets You Will Always Win" series on YouTube, talks about the psychology that makes these bets nearly foolproof.
    Link


    Eat Your Heart Out


    Over the last several decades, it has become accepted wisdom that consuming saturated fat, the type found in meat and butter, is bad for you. Starting in the 1960s, studies showed convincingly that saturated fat raises cholesterol levels and that these elevated levels, especially of low-density lipoprotein cholesterol, or LDL (the so-called bad cholesterol), increase heart disease. Studies also showed that consuming polyunsaturated fats — safflower, corn and soybean oils — reduced people’s levels of overall cholesterol and LDL and should be encouraged.
    But new studies may be upending those assumptions

    Tuesday, March 12, 2013

    The New Power of Memory


    Sharp Recall Skills Prove Key to Future Success; Some Excel at 'Mental Time Travel

    (..)
    Researchers at the University of California, Los Angeles found that students who engaged in detailed simulation of studying for a test—imagining all the steps involved in studying—ended up doing better on the exam than those who simply imagined doing well.

    Hard Math: Adding Up Just How Little We Actually Move


    Working out at the gym might not be enough to stay fit if you spend much of the rest of the day sitting down.
    Americans are more sedentary than ever, government surveys show. That is a problem even among people who exercise regularly.
    (..)
    Americans on average take 5,117 steps a day, according to a 2010 study published in the journal Medicine & Science in Sports & Exercise. A good daily goal, by contrast, is 10,000 steps, according to the American Heart Association and other experts. Research studies have found that such a regimen results in modest weight loss, improved glucose tolerance in people at risk of developing diabetes and other benefits, says David Bassett Jr., co-author of the 2010 study and a professor in the department of kinesiology, recreation and sport studies at the University of Tennessee.
    (..)
    A study that followed more than 240,000 adults over 8½ years found that watching a large amount of television was associated with a higher risk of death, including from cardiovascular disease—even for participants who reported seven or more hours a week of moderate-to-vigorous exercise. The research, published in 2012 in the American Journal of Clinical Nutrition, used TV viewing and overall sitting time as a proxy for sedentary behavior.

    Tuesday, March 05, 2013

    Wanna Play? Computer Gamers Help Push Frontier Of Brain Research


    People can get pretty addicted to computer games. By some estimates, residents of planet Earth spend 3 billion hours per week playing them. Now some scientists are hoping to make use of all that human capital and harness it for a good cause.
    Right now I'm at the novice level of a game called EyeWire, trying to color in a nerve cell in a cartoon drawing of a slice of tissue. EyeWire is designed to solve a real science problem — it aims to chart the billions of nerve connections in the brain,
    (..)
    At least Seung is hoping that's what people will think. But before he tackles the human brain, Seung wants to explore a simpler collection of cells: the ones in the back of the eyes of mice. So he and his colleagues created EyeWire, which looks at the neural connections in the eye. So far about 35,000 people have registered witheyewire.org to play.
    "Anyone sitting in their living room can just fire up a web browser and look at images of neurons, and help us figure out how they're connected," he says.
    Link


    Baby Cured of HIV for the First Time, Researchers Say


    Baby Cured of HIV for the First Time, Researchers Say

    A Mississippi baby born with the AIDS virus appears to have been cured after being treated with an aggressive regimen of drugs just after her birth 2½ years ago, an unusual case that could trigger changes in care for hundreds of thousands of babies born globally each year with HIV.
    The findings, reported Sunday by researchers, mark only the second documented case of a patient being cured of infection with the human immune-deficiency virus. The first, an adult man known as the Berlin patient, was cured as a result of a 2007 bone-marrow transplant.
    (..)
    The chance an infected pregnant woman will transmit the virus to her baby during gestation, birth or breast-feeding ranges from 15% to 45%, according to WHO. But treatment with antiretroviral therapy during pregnancy and especially around the time of birth cuts the risk of mother-to-child transmission to below 2%. Still, estimates are that between 300,000 and 400,000 infants are born globally each year with the infection, about 90% of them in resource-poor countries in sub-Saharan Africa.

    Sunday, March 03, 2013

    It’s the Sugar, Folks


    Sugar is indeed toxic. It may not be the only problem with the Standard American Diet, but it’s fast becoming clear that it’s the major one.
    A study published in the Feb. 27 issue of the journal PLoS One links increased consumption of sugar with increased rates of diabetes by examining the data on sugar availability and the rate of diabetes in 175 countries over the past decade. And after accounting for many other factors, the researchers found that increased sugar in a population’s food supply was linked to higher diabetes rates independent of rates of obesity.

    In other words, according to this study, obesity doesn’t cause diabetes: sugar does.
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