1. 8 predictors (age, sex, education level, race, smoking status, presence of pigment abnormality, soft drusen, and maximum drusen size) were utilized to create a macular risk scoring system (MRSS).
2. Area under the receiver operating characteristic (ROC) curve was excellent (internally validated c-index = 0.88; externally validated c-index = 0.91). Sensitivity and specificity at cutoff of 0 were 87.6% and 73.6% respectively.
Evidence Rating Level: 2 (Good)
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